klhl23 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

klhl23

Kelch-like family member 23. (553 aa)

Predicted Functional Partners:

setd4

0.647

srgap3

0.633

LOC103467401

0.553

bbs9

0.529

ssb

0.520

mib2

0.506

bbs7

0.490

ttc8

0.482

ubxn7

0.431

LOC103470579

0.421

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103467401	klhl23	ENSPREP00000029660	ENSPREP00000005296	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Kelch-like family member 23.	0.553
LOC103467401	setd4	ENSPREP00000029660	ENSPREP00000008256	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	SET domain containing 4.	0.553
LOC103467401	srgap3	ENSPREP00000029660	ENSPREP00000013681	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	SLIT-ROBO Rho GTPase activating protein 3.	0.481
LOC103470579	bbs7	ENSPREP00000013695	ENSPREP00000010413	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Bardet-Biedl syndrome 7.	0.920
LOC103470579	bbs9	ENSPREP00000013695	ENSPREP00000028422	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Bardet-Biedl syndrome 9.	0.909
LOC103470579	klhl23	ENSPREP00000013695	ENSPREP00000005296	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kelch-like family member 23.	0.421
LOC103470579	ttc8	ENSPREP00000013695	ENSPREP00000014316	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Tetratricopeptide repeat domain 8.	0.884
bbs7	LOC103470579	ENSPREP00000010413	ENSPREP00000013695	Bardet-Biedl syndrome 7.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.920
bbs7	bbs9	ENSPREP00000010413	ENSPREP00000028422	Bardet-Biedl syndrome 7.	Bardet-Biedl syndrome 9.	0.997
bbs7	klhl23	ENSPREP00000010413	ENSPREP00000005296	Bardet-Biedl syndrome 7.	Kelch-like family member 23.	0.490
bbs7	ttc8	ENSPREP00000010413	ENSPREP00000014316	Bardet-Biedl syndrome 7.	Tetratricopeptide repeat domain 8.	0.991
bbs9	LOC103470579	ENSPREP00000028422	ENSPREP00000013695	Bardet-Biedl syndrome 9.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.909
bbs9	bbs7	ENSPREP00000028422	ENSPREP00000010413	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 7.	0.997
bbs9	klhl23	ENSPREP00000028422	ENSPREP00000005296	Bardet-Biedl syndrome 9.	Kelch-like family member 23.	0.529
bbs9	ttc8	ENSPREP00000028422	ENSPREP00000014316	Bardet-Biedl syndrome 9.	Tetratricopeptide repeat domain 8.	0.992
klhl23	LOC103467401	ENSPREP00000005296	ENSPREP00000029660	Kelch-like family member 23.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.553
klhl23	LOC103470579	ENSPREP00000005296	ENSPREP00000013695	Kelch-like family member 23.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.421
klhl23	bbs7	ENSPREP00000005296	ENSPREP00000010413	Kelch-like family member 23.	Bardet-Biedl syndrome 7.	0.490
klhl23	bbs9	ENSPREP00000005296	ENSPREP00000028422	Kelch-like family member 23.	Bardet-Biedl syndrome 9.	0.529
klhl23	mib2	ENSPREP00000005296	ENSPREP00000014990	Kelch-like family member 23.	Mindbomb E3 ubiquitin protein ligase 2.	0.506