Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
kcnq1Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (631 aa)    
Predicted Functional Partners:
ENSPREP00000024223
Uncharacterized protein.
    
 0.992
LOC103468785
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.916
LOC103479663
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
    
 0.916
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.916
ENSPREP00000028578
Ion_trans domain-containing protein; Belongs to the potassium channel family.
  
  
 
0.902
LOC103458731
Pericentrin.
    
 0.820
ENSPREP00000018293
Uncharacterized protein.
    
 0.820
akap9
PACT_coil_coil domain-containing protein.
    
 0.820
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
  0.796
Kcne4
Potassium voltage-gated channel, Isk-related family, member 4.
    
 0.723
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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