trim8 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

trim8

Tripartite motif containing 8b. (595 aa)

Predicted Functional Partners:

map3k7

0.778

ENSPREP00000018384

0.778

trim32

0.578

LOC103465723

0.532

LOC103462451

0.532

map3k20

0.504

LOC103479332

0.504

trim23

0.502

Nhp2

0.497

gar1

0.497

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000018384	map3k7	ENSPREP00000018384	ENSPREP00000002180	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 7.	0.901
ENSPREP00000018384	trim8	ENSPREP00000018384	ENSPREP00000005387	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Tripartite motif containing 8b.	0.778
LOC103462451	trim32	ENSPREP00000034047	ENSPREP00000024244	Tripartite motif containing 66.	Tripartite motif containing 32.	0.400
LOC103462451	trim8	ENSPREP00000034047	ENSPREP00000005387	Tripartite motif containing 66.	Tripartite motif containing 8b.	0.532
LOC103465723	trim32	ENSPREP00000006069	ENSPREP00000024244	Uncharacterized protein.	Tripartite motif containing 32.	0.400
LOC103465723	trim8	ENSPREP00000006069	ENSPREP00000005387	Uncharacterized protein.	Tripartite motif containing 8b.	0.532
LOC103479332	map3k20	ENSPREP00000019978	ENSPREP00000007414	Protein kinase domain-containing protein.	Uncharacterized protein.	0.904
LOC103479332	trim8	ENSPREP00000019978	ENSPREP00000005387	Protein kinase domain-containing protein.	Tripartite motif containing 8b.	0.504
Nhp2	gar1	ENSPREP00000007279	ENSPREP00000015416	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.999
Nhp2	trim8	ENSPREP00000007279	ENSPREP00000005387	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	Tripartite motif containing 8b.	0.497
gar1	Nhp2	ENSPREP00000015416	ENSPREP00000007279	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.999
gar1	trim8	ENSPREP00000015416	ENSPREP00000005387	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Tripartite motif containing 8b.	0.497
map3k20	LOC103479332	ENSPREP00000007414	ENSPREP00000019978	Uncharacterized protein.	Protein kinase domain-containing protein.	0.904
map3k20	trim8	ENSPREP00000007414	ENSPREP00000005387	Uncharacterized protein.	Tripartite motif containing 8b.	0.504
map3k7	ENSPREP00000018384	ENSPREP00000002180	ENSPREP00000018384	Mitogen-activated protein kinase kinase kinase 7.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.901
map3k7	trim8	ENSPREP00000002180	ENSPREP00000005387	Mitogen-activated protein kinase kinase kinase 7.	Tripartite motif containing 8b.	0.778
trim23	trim32	ENSPREP00000027307	ENSPREP00000024244	Tripartite motif containing 23.	Tripartite motif containing 32.	0.528
trim23	trim8	ENSPREP00000027307	ENSPREP00000005387	Tripartite motif containing 23.	Tripartite motif containing 8b.	0.502
trim32	LOC103462451	ENSPREP00000024244	ENSPREP00000034047	Tripartite motif containing 32.	Tripartite motif containing 66.	0.400
trim32	LOC103465723	ENSPREP00000024244	ENSPREP00000006069	Tripartite motif containing 32.	Uncharacterized protein.	0.400