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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtn4ip1Reticulon 4 interacting protein 1. (413 aa)    
Predicted Functional Partners:
ca7
Carbonic anhydrase VII; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.600
acadm
Acyl-CoA dehydrogenase medium chain.
  
 0.596
hsdl2
Hydroxysteroid dehydrogenase like 2.
  
 0.589
adhfe1
Alcohol dehydrogenase iron containing 1.
     
 0.561
LOC103456937
Carrier domain-containing protein.
  
 0.558
LOC103456785
Si:dkey-61p9.11.
  
 0.558
fasn
Coiled-coil domain containing 57.
  
 0.558
ppp1r21
Protein phosphatase 1, regulatory subunit 21.
    
   0.555
ENSPREP00000030871
Uncharacterized protein.
      
 0.549
mecr
Mitochondrial trans-2-enoyl-CoA reductase.
  
  
 0.541
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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