ENSPREP00000005404 protein (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSPREP00000005404

Inhibitor of nuclear factor kappa B kinase subunit epsilon. (426 aa)

Predicted Functional Partners:

tank

0.997

LOC103481249

0.997

traf3

0.996

sting1

0.996

irf7

0.981

cyld

0.975

LOC103463417

0.975

LOC103465561

0.975

LOC103480376

0.967

stat1

0.957

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000005404	LOC103463417	ENSPREP00000005404	ENSPREP00000013219	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Cylindromatosis (turban tumor syndrome), like.	0.975
ENSPREP00000005404	LOC103465561	ENSPREP00000005404	ENSPREP00000032899	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Cylindromatosis (turban tumor syndrome), b.	0.975
ENSPREP00000005404	LOC103480376	ENSPREP00000005404	ENSPREP00000013878	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Uncharacterized protein.	0.967
ENSPREP00000005404	LOC103481249	ENSPREP00000005404	ENSPREP00000032515	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Interferon regulatory factor 3.	0.997
ENSPREP00000005404	cyld	ENSPREP00000005404	ENSPREP00000010113	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.975
ENSPREP00000005404	irf7	ENSPREP00000005404	ENSPREP00000028492	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Interferon regulatory factor 7.	0.981
ENSPREP00000005404	stat1	ENSPREP00000005404	ENSPREP00000033192	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Signal transducer and activator of transcription.	0.957
ENSPREP00000005404	sting1	ENSPREP00000005404	ENSPREP00000006284	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Transmembrane protein 173.	0.996
ENSPREP00000005404	tank	ENSPREP00000005404	ENSPREP00000011950	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TRAF family member-associated NFKB activator.	0.997
ENSPREP00000005404	traf3	ENSPREP00000005404	ENSPREP00000006242	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.996
LOC103463417	ENSPREP00000005404	ENSPREP00000013219	ENSPREP00000005404	Cylindromatosis (turban tumor syndrome), like.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.975
LOC103463417	traf3	ENSPREP00000013219	ENSPREP00000006242	Cylindromatosis (turban tumor syndrome), like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.690
LOC103465561	ENSPREP00000005404	ENSPREP00000032899	ENSPREP00000005404	Cylindromatosis (turban tumor syndrome), b.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.975
LOC103465561	traf3	ENSPREP00000032899	ENSPREP00000006242	Cylindromatosis (turban tumor syndrome), b.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.690
LOC103480376	ENSPREP00000005404	ENSPREP00000013878	ENSPREP00000005404	Uncharacterized protein.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.967
LOC103480376	traf3	ENSPREP00000013878	ENSPREP00000006242	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.659
LOC103481249	ENSPREP00000005404	ENSPREP00000032515	ENSPREP00000005404	Interferon regulatory factor 3.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.997
LOC103481249	irf7	ENSPREP00000032515	ENSPREP00000028492	Interferon regulatory factor 3.	Interferon regulatory factor 7.	0.962
LOC103481249	stat1	ENSPREP00000032515	ENSPREP00000033192	Interferon regulatory factor 3.	Signal transducer and activator of transcription.	0.714
LOC103481249	sting1	ENSPREP00000032515	ENSPREP00000006284	Interferon regulatory factor 3.	Transmembrane protein 173.	0.992