LOC103477204 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC103477204

Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (351 aa)

Predicted Functional Partners:

nsmce2

0.999

nsmce1

0.998

LOC103468053

0.998

smc5

0.995

smc6

0.984

LOC103458344

0.984

LOC103466839

0.946

ENSPREP00000027924

0.915

ENSPREP00000029155

0.915

smc3

0.848

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000027924	LOC103458344	ENSPREP00000027924	ENSPREP00000025027	Uncharacterized protein.	Structural maintenance of chromosomes 6.	0.841
ENSPREP00000027924	LOC103466839	ENSPREP00000027924	ENSPREP00000000371	Uncharacterized protein.	Calcyon neuron-specific vesicular protein.	0.844
ENSPREP00000027924	LOC103477204	ENSPREP00000027924	ENSPREP00000005419	Uncharacterized protein.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.915
ENSPREP00000027924	nsmce1	ENSPREP00000027924	ENSPREP00000000366	Uncharacterized protein.	NSE1 homolog, SMC5-SMC6 complex component.	0.844
ENSPREP00000027924	nsmce2	ENSPREP00000027924	ENSPREP00000018674	Uncharacterized protein.	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.	0.897
ENSPREP00000027924	smc3	ENSPREP00000027924	ENSPREP00000000387	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.612
ENSPREP00000027924	smc5	ENSPREP00000027924	ENSPREP00000033520	Uncharacterized protein.	Structural maintenance of chromosomes 5.	0.901
ENSPREP00000027924	smc6	ENSPREP00000027924	ENSPREP00000002658	Uncharacterized protein.	Si:dkey-119f1.1.	0.841
ENSPREP00000029155	LOC103458344	ENSPREP00000029155	ENSPREP00000025027	Uncharacterized protein.	Structural maintenance of chromosomes 6.	0.841
ENSPREP00000029155	LOC103466839	ENSPREP00000029155	ENSPREP00000000371	Uncharacterized protein.	Calcyon neuron-specific vesicular protein.	0.844
ENSPREP00000029155	LOC103477204	ENSPREP00000029155	ENSPREP00000005419	Uncharacterized protein.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.915
ENSPREP00000029155	nsmce1	ENSPREP00000029155	ENSPREP00000000366	Uncharacterized protein.	NSE1 homolog, SMC5-SMC6 complex component.	0.844
ENSPREP00000029155	nsmce2	ENSPREP00000029155	ENSPREP00000018674	Uncharacterized protein.	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.	0.897
ENSPREP00000029155	smc3	ENSPREP00000029155	ENSPREP00000000387	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.612
ENSPREP00000029155	smc5	ENSPREP00000029155	ENSPREP00000033520	Uncharacterized protein.	Structural maintenance of chromosomes 5.	0.901
ENSPREP00000029155	smc6	ENSPREP00000029155	ENSPREP00000002658	Uncharacterized protein.	Si:dkey-119f1.1.	0.841
LOC103458344	ENSPREP00000027924	ENSPREP00000025027	ENSPREP00000027924	Structural maintenance of chromosomes 6.	Uncharacterized protein.	0.841
LOC103458344	ENSPREP00000029155	ENSPREP00000025027	ENSPREP00000029155	Structural maintenance of chromosomes 6.	Uncharacterized protein.	0.841
LOC103458344	LOC103466839	ENSPREP00000025027	ENSPREP00000000371	Structural maintenance of chromosomes 6.	Calcyon neuron-specific vesicular protein.	0.887
LOC103458344	LOC103468053	ENSPREP00000025027	ENSPREP00000002796	Structural maintenance of chromosomes 6.	Necdin-like 2.	0.964

page 1 of 6

Server load: low (26%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About