Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bag6BCL2 associated athanogene 6. (1194 aa)    
Predicted Functional Partners:
get4
Guided entry of tail-anchored proteins factor 4.
    
 0.995
LOC103470505
Ubiquitin like 4A.
    
0.992
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
    
 0.987
ubxn1
UBX domain protein 1.
    
 
 0.970
faf2
Fas associated factor family member 2.
    
 
 0.963
sgta
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha.
   
 0.955
sgtb
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta.
   
 0.937
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.933
rnf126
RING-type domain-containing protein.
   
 
 0.926
LOC103479460
Ring finger protein 126.
   
 
 0.926
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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