Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fnip1Folliculin interacting protein 1. (1222 aa)    
Predicted Functional Partners:
flcn
Folliculin.
    
 0.999
LOC103475719
Ras-related GTP binding A.
    
 0.968
rragc
Ras-related GTP binding Ca.
   
 
 0.966
LOC103473076
Uncharacterized protein.
   
 
 0.966
fem1b
Fem-1 homolog b (C. elegans).
    
 0.954
atp6v1d
ATPase H+ transporting V1 subunit D.
    
 0.899
stip1
Stress-induced phosphoprotein 1.
   
 0.828
lamtor2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
     
 0.817
LOC103472369
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
   
 
 0.747
atp6v1c1
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
   
 
 0.747
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (12%) [HD]