dyrk3 protein (Poecilia reticulata) - STRING interaction network

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Score

dyrk3

Dual specificity tyrosine phosphorylation regulated kinase 3. (598 aa)

Predicted Functional Partners:

tp53

0.798

atm

0.752

DCAF7

0.681

mdm2

0.681

LOC103464804

0.680

DCAF1

0.680

ubr5

0.641

rps27a

0.639

ddb1

0.629

fbxw11

0.576

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCAF1	LOC103464804	ENSPREP00000025564	ENSPREP00000022084	DDB1 and CUL4 associated factor 1.	LisH domain-containing protein.	0.547
DCAF1	ddb1	ENSPREP00000025564	ENSPREP00000006475	DDB1 and CUL4 associated factor 1.	Damage-specific DNA binding protein 1.	0.964
DCAF1	dyrk3	ENSPREP00000025564	ENSPREP00000005510	DDB1 and CUL4 associated factor 1.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.680
DCAF1	rps27a	ENSPREP00000025564	ENSPREP00000018427	DDB1 and CUL4 associated factor 1.	Ribosomal protein S27a.	0.484
DCAF1	tp53	ENSPREP00000025564	ENSPREP00000019676	DDB1 and CUL4 associated factor 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.574
DCAF7	ddb1	ENSPREP00000015057	ENSPREP00000006475	DDB1 and CUL4 associated factor 7.	Damage-specific DNA binding protein 1.	0.986
DCAF7	dyrk3	ENSPREP00000015057	ENSPREP00000005510	DDB1 and CUL4 associated factor 7.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.681
LOC103464804	DCAF1	ENSPREP00000022084	ENSPREP00000025564	LisH domain-containing protein.	DDB1 and CUL4 associated factor 1.	0.547
LOC103464804	ddb1	ENSPREP00000022084	ENSPREP00000006475	LisH domain-containing protein.	Damage-specific DNA binding protein 1.	0.964
LOC103464804	dyrk3	ENSPREP00000022084	ENSPREP00000005510	LisH domain-containing protein.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.680
LOC103464804	rps27a	ENSPREP00000022084	ENSPREP00000018427	LisH domain-containing protein.	Ribosomal protein S27a.	0.484
LOC103464804	tp53	ENSPREP00000022084	ENSPREP00000019676	LisH domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.574
atm	ddb1	ENSPREP00000024388	ENSPREP00000006475	Non-specific serine/threonine protein kinase.	Damage-specific DNA binding protein 1.	0.503
atm	dyrk3	ENSPREP00000024388	ENSPREP00000005510	Non-specific serine/threonine protein kinase.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.752
atm	mdm2	ENSPREP00000024388	ENSPREP00000032347	Non-specific serine/threonine protein kinase.	MDM2 proto-oncogene.	0.997
atm	rps27a	ENSPREP00000024388	ENSPREP00000018427	Non-specific serine/threonine protein kinase.	Ribosomal protein S27a.	0.934
atm	tp53	ENSPREP00000024388	ENSPREP00000019676	Non-specific serine/threonine protein kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.999
ddb1	DCAF1	ENSPREP00000006475	ENSPREP00000025564	Damage-specific DNA binding protein 1.	DDB1 and CUL4 associated factor 1.	0.964
ddb1	DCAF7	ENSPREP00000006475	ENSPREP00000015057	Damage-specific DNA binding protein 1.	DDB1 and CUL4 associated factor 7.	0.986
ddb1	LOC103464804	ENSPREP00000006475	ENSPREP00000022084	Damage-specific DNA binding protein 1.	LisH domain-containing protein.	0.964