STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103478660Ankyrin repeat domain 50-like. (1391 aa)    
Predicted Functional Partners:
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.717
LOC103474066
Serine/threonine-protein phosphatase.
    
 0.661
PPP6C
Serine/threonine-protein phosphatase.
    
 0.661
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.624
aup1
AUP1 lipid droplet regulating VLDL assembly factor.
    
 
 0.604
ppp6r2
Protein phosphatase 6, regulatory subunit 2b.
    
 0.549
ppp6r3
Protein phosphatase 6, regulatory subunit 3.
    
 0.549
LOC103459548
Protein phosphatase 6, regulatory subunit 2a.
    
 0.549
arl13b
ADP-ribosylation factor-like 13b.
    
  0.490
tbc1d23
TBC1 domain family, member 23.
      
 0.460
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.