STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
map4k2Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (809 aa)    
Predicted Functional Partners:
LOC103469572
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
  0.906
LOC103473816
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
  0.906
nf2
Neurofibromin 2b (merlin).
   
  
 0.602
grap2
GRB2 related adaptor protein 2a.
   
 
 0.589
grb2
Growth factor receptor-bound protein 2b.
   
 
 0.578
wwc3
WWC family member 3.
      
 0.565
LOC103475719
Ras-related GTP binding A.
    
 
 0.524
ENSPREP00000004399
CNH domain-containing protein.
 
      0.419
rragc
Ras-related GTP binding Ca.
    
 
 0.410
LOC103473076
Uncharacterized protein.
    
 
 0.410
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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