Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iars2Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1098 aa)    
Predicted Functional Partners:
eprs1
Glutamyl-prolyl-tRNA synthetase.
  
 0.999
mars1
Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.965
pars2
Prolyl-tRNA synthetase 2, mitochondrial.
   
 0.965
yars1
Tyrosine--tRNA ligase.
  
 0.963
kars1
Lysine--tRNA ligase.
  
 0.945
vars2
Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.941
lars1
Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.940
rars2
Arginyl-tRNA synthetase 2, mitochondrial (putative); Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.930
lars2
Leucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.925
rars1
Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.924
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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