LOC103477863 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC103477863

RAB5A, member RAS oncogene family, b. (216 aa)

Predicted Functional Partners:

LOC103474679

0.989

RABGEF1

0.989

LOC103470250

0.989

pik3c3

0.972

rbsn

0.904

vps18

0.886

vps16

0.877

eea1

0.863

vps11

0.851

tgfbrap1

0.845

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103470250	LOC103474679	ENSPREP00000030738	ENSPREP00000002413	Uncharacterized protein.	RAB guanine nucleotide exchange factor (GEF) 1, like.	0.954
LOC103470250	LOC103477863	ENSPREP00000030738	ENSPREP00000005592	Uncharacterized protein.	RAB5A, member RAS oncogene family, b.	0.989
LOC103470250	RABGEF1	ENSPREP00000030738	ENSPREP00000008918	Uncharacterized protein.	RAB guanine nucleotide exchange factor 1.	0.954
LOC103470250	rbsn	ENSPREP00000030738	ENSPREP00000024815	Uncharacterized protein.	Rabenosyn, RAB effector.	0.549
LOC103470250	vps11	ENSPREP00000030738	ENSPREP00000020294	Uncharacterized protein.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.444
LOC103474679	LOC103470250	ENSPREP00000002413	ENSPREP00000030738	RAB guanine nucleotide exchange factor (GEF) 1, like.	Uncharacterized protein.	0.954
LOC103474679	LOC103477863	ENSPREP00000002413	ENSPREP00000005592	RAB guanine nucleotide exchange factor (GEF) 1, like.	RAB5A, member RAS oncogene family, b.	0.989
LOC103474679	RABGEF1	ENSPREP00000002413	ENSPREP00000008918	RAB guanine nucleotide exchange factor (GEF) 1, like.	RAB guanine nucleotide exchange factor 1.	0.953
LOC103474679	rbsn	ENSPREP00000002413	ENSPREP00000024815	RAB guanine nucleotide exchange factor (GEF) 1, like.	Rabenosyn, RAB effector.	0.541
LOC103474679	tgfbrap1	ENSPREP00000002413	ENSPREP00000031620	RAB guanine nucleotide exchange factor (GEF) 1, like.	Transforming growth factor, beta receptor associated protein 1.	0.401
LOC103474679	vps11	ENSPREP00000002413	ENSPREP00000020294	RAB guanine nucleotide exchange factor (GEF) 1, like.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.444
LOC103477863	LOC103470250	ENSPREP00000005592	ENSPREP00000030738	RAB5A, member RAS oncogene family, b.	Uncharacterized protein.	0.989
LOC103477863	LOC103474679	ENSPREP00000005592	ENSPREP00000002413	RAB5A, member RAS oncogene family, b.	RAB guanine nucleotide exchange factor (GEF) 1, like.	0.989
LOC103477863	RABGEF1	ENSPREP00000005592	ENSPREP00000008918	RAB5A, member RAS oncogene family, b.	RAB guanine nucleotide exchange factor 1.	0.989
LOC103477863	eea1	ENSPREP00000005592	ENSPREP00000026591	RAB5A, member RAS oncogene family, b.	Early endosome antigen 1.	0.863
LOC103477863	pik3c3	ENSPREP00000005592	ENSPREP00000005530	RAB5A, member RAS oncogene family, b.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.972
LOC103477863	rbsn	ENSPREP00000005592	ENSPREP00000024815	RAB5A, member RAS oncogene family, b.	Rabenosyn, RAB effector.	0.904
LOC103477863	tgfbrap1	ENSPREP00000005592	ENSPREP00000031620	RAB5A, member RAS oncogene family, b.	Transforming growth factor, beta receptor associated protein 1.	0.845
LOC103477863	vps11	ENSPREP00000005592	ENSPREP00000020294	RAB5A, member RAS oncogene family, b.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.851
LOC103477863	vps16	ENSPREP00000005592	ENSPREP00000016077	RAB5A, member RAS oncogene family, b.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.877