STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC103466897Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)    
Predicted Functional Partners:
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 0.998
LOC103468393
Phosphoinositide-3-kinase regulatory subunit 5.
   
 0.972
ENSPREP00000025109
Uncharacterized protein.
    
  0.930
pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
  
  
 
0.903
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.896
gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.896
LOC103474789
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.873
LOC103476681
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.873
LOC103470003
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.873
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.873
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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