ubr3 protein (Poecilia reticulata) - STRING interaction network

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ubr3

E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1855 aa)

Predicted Functional Partners:

hectd1

0.786

mipep

0.670

cul5

0.609

CUL5

0.609

ENSPREP00000019127

0.604

trip12

0.602

ubr7

0.595

ube2b

0.563

ube2a

0.563

LOC103459783

0.563

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL5	cul5	ENSPREP00000025561	ENSPREP00000024104	Cullin 5; Belongs to the cullin family.	Cullin 5; Belongs to the cullin family.	0.901
CUL5	trip12	ENSPREP00000025561	ENSPREP00000026747	Cullin 5; Belongs to the cullin family.	Thyroid hormone receptor interactor 12.	0.468
CUL5	ubr3	ENSPREP00000025561	ENSPREP00000005613	Cullin 5; Belongs to the cullin family.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.609
ENSPREP00000019127	ubr3	ENSPREP00000019127	ENSPREP00000005613	Uncharacterized protein.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.604
LOC103459783	trip12	ENSPREP00000033554	ENSPREP00000026747	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	Thyroid hormone receptor interactor 12.	0.900
LOC103459783	ube2a	ENSPREP00000033554	ENSPREP00000018234	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.979
LOC103459783	ube2b	ENSPREP00000033554	ENSPREP00000007643	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.801
LOC103459783	ubr3	ENSPREP00000033554	ENSPREP00000005613	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.563
cul5	CUL5	ENSPREP00000024104	ENSPREP00000025561	Cullin 5; Belongs to the cullin family.	Cullin 5; Belongs to the cullin family.	0.901
cul5	trip12	ENSPREP00000024104	ENSPREP00000026747	Cullin 5; Belongs to the cullin family.	Thyroid hormone receptor interactor 12.	0.468
cul5	ubr3	ENSPREP00000024104	ENSPREP00000005613	Cullin 5; Belongs to the cullin family.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.609
hectd1	trip12	ENSPREP00000004547	ENSPREP00000026747	HECT domain containing 1.	Thyroid hormone receptor interactor 12.	0.821
hectd1	ubr3	ENSPREP00000004547	ENSPREP00000005613	HECT domain containing 1.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.786
mipep	ubr3	ENSPREP00000023938	ENSPREP00000005613	Mitochondrial intermediate peptidase.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.670
trip12	CUL5	ENSPREP00000026747	ENSPREP00000025561	Thyroid hormone receptor interactor 12.	Cullin 5; Belongs to the cullin family.	0.468
trip12	LOC103459783	ENSPREP00000026747	ENSPREP00000033554	Thyroid hormone receptor interactor 12.	Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.	0.900
trip12	cul5	ENSPREP00000026747	ENSPREP00000024104	Thyroid hormone receptor interactor 12.	Cullin 5; Belongs to the cullin family.	0.468
trip12	hectd1	ENSPREP00000026747	ENSPREP00000004547	Thyroid hormone receptor interactor 12.	HECT domain containing 1.	0.821
trip12	ube2a	ENSPREP00000026747	ENSPREP00000018234	Thyroid hormone receptor interactor 12.	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.900
trip12	ube2b	ENSPREP00000026747	ENSPREP00000007643	Thyroid hormone receptor interactor 12.	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.900

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