Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
F2rl2Coagulation factor II (thrombin) receptor-like 2. (377 aa)    
Predicted Functional Partners:
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.978
LOC103464916
Si:dkey-33m11.7; Belongs to the peptidase S1 family.
    
  0.721
LOC103478476
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
  0.721
LOC103478467
Serine protease 1; Belongs to the peptidase S1 family.
    
  0.721
LOC103469978
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
  0.721
LOC108166573
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
  0.721
LOC103470643
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
  0.721
LOC103469980
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
  0.721
LOC103478116
Serine protease 59, tandem duplicate 1; Belongs to the peptidase S1 family.
    
  0.721
LOC103477911
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
  0.721
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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