Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103475332Interferon regulatory factor. (291 aa)    
Predicted Functional Partners:
stub1
STIP1 homology and U-Box containing protein 1.
    
 
 0.969
LOC103468460
E1A binding protein p300 b.
    
 0.929
LOC103482005
E1A binding protein p300 a.
    
 0.929
stat1
Signal transducer and activator of transcription.
   
 0.925
mdm2
MDM2 proto-oncogene.
    
 0.915
LOC103471006
Interferon regulatory factor 2.
   
 0.903
LOC103465382
Signal transducer and activator of transcription.
   
 0.855
stat3
Signal transducer and activator of transcription.
   
 0.835
LOC103460697
STAT_int domain-containing protein.
   
 0.770
ENSPREP00000008903
SH2 domain-containing protein.
   
 0.770
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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