STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F2rCoagulation factor II (thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (436 aa)    
Predicted Functional Partners:
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
  0.957
gna12
G protein subunit alpha 12.
    
 0.913
LOC103481631
Uncharacterized protein.
    
 0.913
LOC103468273
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.913
LOC103473499
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
  
  
 
0.903
LOC103470235
Uncharacterized protein.
    
 0.744
LOC103464916
Si:dkey-33m11.7; Belongs to the peptidase S1 family.
    
 0.718
LOC103478116
Serine protease 59, tandem duplicate 1; Belongs to the peptidase S1 family.
    
 0.718
LOC103467819
Zmp:0000001088; Belongs to the peptidase S1 family.
    
 0.718
LOC103478476
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.714
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.