close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maddMAP-kinase activating death domain. (1673 aa)    
Predicted Functional Partners:
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.726
LOC103459897
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
 0.656
ENSPREP00000001350
Uncharacterized protein.
     
 0.619
rab27a
RAB27A, member RAS oncogene family.
     
 0.619
LOC103469909
Uncharacterized protein.
     
 0.619
RAB27B
RAB27B, member RAS oncogene family.
     
 0.619
LOC103463266
RAB3B, member RAS oncogene family.
    
 0.590
LOC103479175
RAB3A, member RAS oncogene family, b.
    
 0.590
LOC103463328
RAB3A, member RAS oncogene family, b.
    
 0.590
rab3d
RAB3D, member RAS oncogene family, b.
    
 0.590
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (20%) [HD]