STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
maddMAP-kinase activating death domain. (1673 aa)    
Predicted Functional Partners:
dennd1a
DENN/MADD domain containing 1A.
    
 
 0.807
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.774
ENSPREP00000001350
Uncharacterized protein.
     
 0.692
rab27a
RAB27A, member RAS oncogene family.
     
 0.692
LOC103469909
Uncharacterized protein.
     
 0.692
RAB27B
RAB27B, member RAS oncogene family.
     
 0.692
dennd5a
DENN/MADD domain containing 5A.
    
 
 0.646
LOC103459897
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
 0.631
rab3gap1
RAB3 GTPase activating protein subunit 1.
   
  
 0.624
LOC103463266
RAB3B, member RAS oncogene family.
    
 0.621
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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