creb1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

creb1

Uncharacterized protein. (331 aa)

Predicted Functional Partners:

rps6ka5

0.970

LOC103468460

0.948

LOC103482005

0.948

LOC103464091

0.944

crebbp

0.944

LOC103479464

0.902

LOC103473381

0.900

LOC103468785

0.784

LOC103479663

0.784

prkacb

0.784

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464091	LOC103468460	ENSPREP00000000408	ENSPREP00000026558	CREB binding protein a.	E1A binding protein p300 b.	0.998
LOC103464091	LOC103468785	ENSPREP00000000408	ENSPREP00000006192	CREB binding protein a.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.708
LOC103464091	LOC103473381	ENSPREP00000000408	ENSPREP00000024999	CREB binding protein a.	cAMP responsive element binding protein 1.	0.944
LOC103464091	LOC103479464	ENSPREP00000000408	ENSPREP00000026997	CREB binding protein a.	Uncharacterized protein.	0.732
LOC103464091	LOC103479663	ENSPREP00000000408	ENSPREP00000014181	CREB binding protein a.	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	0.708
LOC103464091	LOC103482005	ENSPREP00000000408	ENSPREP00000030842	CREB binding protein a.	E1A binding protein p300 a.	0.998
LOC103464091	creb1	ENSPREP00000000408	ENSPREP00000005794	CREB binding protein a.	Uncharacterized protein.	0.944
LOC103464091	crebbp	ENSPREP00000000408	ENSPREP00000011232	CREB binding protein a.	CREB binding protein b.	0.901
LOC103464091	prkacb	ENSPREP00000000408	ENSPREP00000021366	CREB binding protein a.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.708
LOC103468460	LOC103464091	ENSPREP00000026558	ENSPREP00000000408	E1A binding protein p300 b.	CREB binding protein a.	0.998
LOC103468460	LOC103468785	ENSPREP00000026558	ENSPREP00000006192	E1A binding protein p300 b.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.682
LOC103468460	LOC103473381	ENSPREP00000026558	ENSPREP00000024999	E1A binding protein p300 b.	cAMP responsive element binding protein 1.	0.948
LOC103468460	LOC103479464	ENSPREP00000026558	ENSPREP00000026997	E1A binding protein p300 b.	Uncharacterized protein.	0.755
LOC103468460	LOC103479663	ENSPREP00000026558	ENSPREP00000014181	E1A binding protein p300 b.	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	0.682
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103468460	creb1	ENSPREP00000026558	ENSPREP00000005794	E1A binding protein p300 b.	Uncharacterized protein.	0.948
LOC103468460	crebbp	ENSPREP00000026558	ENSPREP00000011232	E1A binding protein p300 b.	CREB binding protein b.	0.998
LOC103468460	prkacb	ENSPREP00000026558	ENSPREP00000021366	E1A binding protein p300 b.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.682
LOC103468785	LOC103464091	ENSPREP00000006192	ENSPREP00000000408	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	CREB binding protein a.	0.708
LOC103468785	LOC103468460	ENSPREP00000006192	ENSPREP00000026558	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	E1A binding protein p300 b.	0.682