STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dact1Uncharacterized protein. (849 aa)    
Predicted Functional Partners:
dvl2
Dishevelled segment polarity protein 2.
    
 0.900
Sestd1
Uncharacterized protein.
    
 
 0.865
ENSPREP00000001242
DIX domain-containing protein.
    
 0.858
ENSPREP00000001400
Uncharacterized protein.
    
 0.858
dvl1
Dishevelled segment polarity protein 1a.
    
 0.858
LOC103479347
Dishevelled segment polarity protein 3a.
    
 0.858
ENSPREP00000020826
DIX domain-containing protein.
    
 0.858
kiaa0586
Uncharacterized protein.
      
 0.765
VANGL1
Vang-like protein.
    
 
 0.740
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.736
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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