poln protein (Poecilia reticulata) - STRING interaction network

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second shell of interactors

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[Homology]

Score

poln

Polymerase (DNA directed) nu. (1294 aa)

Predicted Functional Partners:

helq

0.934

fancd2

0.861

pcna

0.850

fancm

0.779

rad50

0.769

rad51

0.757

parp1

0.744

fan1

0.744

ercc1

0.739

mus81

0.734

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ercc1	fan1	ENSPREP00000015481	ENSPREP00000022191	Excision repair cross-complementation group 1.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.825
ercc1	fancd2	ENSPREP00000015481	ENSPREP00000014095	Excision repair cross-complementation group 1.	FA complementation group D2.	0.929
ercc1	fancm	ENSPREP00000015481	ENSPREP00000029321	Excision repair cross-complementation group 1.	Uncharacterized protein.	0.994
ercc1	helq	ENSPREP00000015481	ENSPREP00000018606	Excision repair cross-complementation group 1.	Helicase, POLQ like.	0.662
ercc1	mus81	ENSPREP00000015481	ENSPREP00000023348	Excision repair cross-complementation group 1.	MUS81 structure-specific endonuclease subunit.	0.997
ercc1	parp1	ENSPREP00000015481	ENSPREP00000001596	Excision repair cross-complementation group 1.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.732
ercc1	pcna	ENSPREP00000015481	ENSPREP00000018020	Excision repair cross-complementation group 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.850
ercc1	poln	ENSPREP00000015481	ENSPREP00000005887	Excision repair cross-complementation group 1.	Polymerase (DNA directed) nu.	0.739
ercc1	rad50	ENSPREP00000015481	ENSPREP00000008829	Excision repair cross-complementation group 1.	RAD50 homolog, double strand break repair protein.	0.783
ercc1	rad51	ENSPREP00000015481	ENSPREP00000001621	Excision repair cross-complementation group 1.	RAD51 recombinase.	0.738
fan1	ercc1	ENSPREP00000022191	ENSPREP00000015481	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Excision repair cross-complementation group 1.	0.825
fan1	fancd2	ENSPREP00000022191	ENSPREP00000014095	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group D2.	0.999
fan1	fancm	ENSPREP00000022191	ENSPREP00000029321	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Uncharacterized protein.	0.899
fan1	helq	ENSPREP00000022191	ENSPREP00000018606	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Helicase, POLQ like.	0.667
fan1	mus81	ENSPREP00000022191	ENSPREP00000023348	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	MUS81 structure-specific endonuclease subunit.	0.847
fan1	pcna	ENSPREP00000022191	ENSPREP00000018020	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.866
fan1	poln	ENSPREP00000022191	ENSPREP00000005887	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Polymerase (DNA directed) nu.	0.744
fancd2	ercc1	ENSPREP00000014095	ENSPREP00000015481	FA complementation group D2.	Excision repair cross-complementation group 1.	0.929
fancd2	fan1	ENSPREP00000014095	ENSPREP00000022191	FA complementation group D2.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.999
fancd2	fancm	ENSPREP00000014095	ENSPREP00000029321	FA complementation group D2.	Uncharacterized protein.	0.999