Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gnat1Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1. (350 aa)    
Predicted Functional Partners:
LOC103472243
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.988
LOC103464516
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
   
 0.987
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
   
 0.987
LOC103481632
Regulator of G protein signaling 9b.
   
 0.965
LOC103468274
Regulator of G protein signaling 9a.
   
 0.965
LOC103464572
Rhodopsin.
   
 0.964
LOC103464571
Rhodopsin.
   
 0.964
RHO
Extra-ocular rhodopsin.
   
 0.964
rho
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
   
 0.964
pde6a
Phosphodiesterase.
   
 0.929
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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