STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)    
Predicted Functional Partners:
ptch2
Patched 2.
    
 0.996
ptch1
Patched 1.
    
 0.994
EVC2
EvC ciliary complex subunit 2.
     
 0.979
EVC
EvC ciliary complex subunit 1.
     
 0.979
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
     
 0.975
arrb2
Arrestin, beta 2a.
    
 0.967
LOC103473184
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    
 0.967
prkaca
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.944
LOC103468785
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.944
LOC103479663
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
    
 0.944
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.