STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edem1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (638 aa)    
Predicted Functional Partners:
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 
 0.836
dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10.
    
 
 0.751
xbp1
X-box binding protein 1.
     
 0.722
LOC103463800
Calmegin.
   
 
 0.644
canx
Calnexin.
   
 
 0.644
pdia5
Protein disulfide isomerase family A, member 5.
    
 
 0.641
derl2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 
 0.605
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 
 0.583
dnajc3
DnaJ (Hsp40) homolog, subfamily C, member 3a.
   
 
 0.581
man2c1
Mannosidase, alpha, class 2C, member 1.
      
 0.549
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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