STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103465726Asp_protease domain-containing protein. (272 aa)    
Predicted Functional Partners:
tbc1d30
TBC1 domain family, member 30.
    
 
 0.749
LOC103464527
DNA-damage inducible protein 2.
    
   0.728
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.712
Rad23a
Ubiquitin-like domain-containing protein.
   
 
 0.669
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 
 0.669
rnf182
Ring finger protein 182.
   
  
 0.615
LOC103478144
Proteasome 26S subunit, non-ATPase 4b.
   
 
 0.606
LOC103472718
Proteasome 26S subunit, non-ATPase 4a.
   
 
 0.606
LOC103466238
Uncharacterized protein.
      
 0.604
rtf2
Replication termination factor 2.
      
 0.601
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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