STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nrg2Neuregulin 2b. (712 aa)    
Predicted Functional Partners:
LOC103461563
Receptor protein-tyrosine kinase.
    
 0.973
erbb3
Protein kinase domain-containing protein.
    
 0.973
erbb4
Receptor protein-tyrosine kinase.
    
 0.972
LOC103467364
Erb-b2 receptor tyrosine kinase 3b.
    
 0.972
LOC103475452
Neuregulin 2a.
  
  
 
0.901
egfr
Receptor protein-tyrosine kinase.
    
 0.771
ENSPREP00000034025
Erb-b2 receptor tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.770
ENSPREP00000034033
Uncharacterized protein.
    
 0.770
egf
Epidermal growth factor.
    
 0.760
EGFR
Receptor protein-tyrosine kinase.
    
 0.739
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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