mat2b protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

mat2b

Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (325 aa)

Predicted Functional Partners:

LOC103476873

0.954

mtr

0.944

LOC103473691

0.944

LOC103473263

0.944

LOC103470277

0.944

LOC103470081

0.943

LOC103470080

0.943

LOC103473309

0.943

amd1

0.923

LOC103463929

0.913

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103463929	LOC103470080	ENSPREP00000025068	ENSPREP00000019019	Zgc:172121.	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	0.902
LOC103463929	LOC103470081	ENSPREP00000025068	ENSPREP00000019002	Zgc:172121.	Hcy-binding domain-containing protein.	0.902
LOC103463929	LOC103470277	ENSPREP00000025068	ENSPREP00000031739	Zgc:172121.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.957
LOC103463929	LOC103473263	ENSPREP00000025068	ENSPREP00000026720	Zgc:172121.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.957
LOC103463929	LOC103473309	ENSPREP00000025068	ENSPREP00000028249	Zgc:172121.	Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism.	0.902
LOC103463929	LOC103473691	ENSPREP00000025068	ENSPREP00000015701	Zgc:172121.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.957
LOC103463929	LOC103476873	ENSPREP00000025068	ENSPREP00000027034	Zgc:172121.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.957
LOC103463929	amd1	ENSPREP00000025068	ENSPREP00000030244	Zgc:172121.	S-adenosylmethionine decarboxylase proenzyme.	0.431
LOC103463929	mat2b	ENSPREP00000025068	ENSPREP00000006040	Zgc:172121.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.913
LOC103463929	mtr	ENSPREP00000025068	ENSPREP00000003676	Zgc:172121.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.906
LOC103470080	LOC103463929	ENSPREP00000019019	ENSPREP00000025068	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	Zgc:172121.	0.902
LOC103470080	LOC103470081	ENSPREP00000019019	ENSPREP00000019002	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	Hcy-binding domain-containing protein.	0.900
LOC103470080	LOC103470277	ENSPREP00000019019	ENSPREP00000031739	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.951
LOC103470080	LOC103473263	ENSPREP00000019019	ENSPREP00000026720	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.951
LOC103470080	LOC103473309	ENSPREP00000019019	ENSPREP00000028249	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism.	0.900
LOC103470080	LOC103473691	ENSPREP00000019019	ENSPREP00000015701	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.951
LOC103470080	LOC103476873	ENSPREP00000019019	ENSPREP00000027034	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.951
LOC103470080	mat2b	ENSPREP00000019019	ENSPREP00000006040	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.943
LOC103470080	mtr	ENSPREP00000019019	ENSPREP00000003676	Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.950
LOC103470081	LOC103463929	ENSPREP00000019002	ENSPREP00000025068	Hcy-binding domain-containing protein.	Zgc:172121.	0.902

page 1 of 5

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About