STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103472181IRS-type PTB domain-containing protein. (505 aa)    
Predicted Functional Partners:
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.530
crk
CRK proto-oncogene, adaptor protein.
    
 0.530
ENSPREP00000023825
SH2 domain-containing protein.
    
 0.530
gab1
GRB2-associated binding protein 1.
    
 0.435
LOC103480707
PH domain-containing protein.
    
 0.435
ENSPREP00000009325
GRB2 related adaptor protein b.
    
 0.429
ENSPREP00000009358
Uncharacterized protein.
    
 0.429
ptpn6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.429
LOC103467098
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.429
grap2
GRB2 related adaptor protein 2a.
    
 0.429
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.