Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMCC3Transmembrane and coiled-coil domain family 3. (481 aa)    
Predicted Functional Partners:
tmcc2
Transmembrane and coiled-coil domain family 2.
   
 
 0.596
LOC103465132
Transmembrane and coiled-coil domain family 1b.
   
 
 0.596
TMCC1
Transmembrane and coiled-coil domain family 1.
   
 
 0.596
tmtc4
Transmembrane O-mannosyltransferase targeting cadherins 4.
      
 0.513
atp2b3
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
      
 0.477
atp2b2
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
      
 0.477
erc2
ELKS/RAB6-interacting/CAST family member 2.
      
 0.477
ERC2
Uncharacterized protein.
      
 0.477
fam161a
FAM161 centrosomal protein A.
    
 
 0.416
thg1l
tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
      
 0.413
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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