Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Experiments
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[Homology]
Score
adnpActivity-dependent neuroprotector homeobox b. (1057 aa)    
Predicted Functional Partners:
zmym2
Zinc finger, MYM-type 2.
   
 
 0.749
LOC103472838
Chromodomain helicase DNA binding protein 4a.
   
 
 0.721
aire
Autoimmune regulator.
   
 
 0.721
chd3
Chromodomain helicase DNA binding protein 3.
   
 
 0.721
chd4
Uncharacterized protein.
   
 
 0.721
chd5
Uncharacterized protein.
   
 
 0.721
trip12
Thyroid hormone receptor interactor 12.
   
  
 0.720
chd8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
   
 
 0.705
LOC103472202
Chromobox homolog 3a (HP1 gamma homolog, Drosophila).
    
 
 0.691
CBX1
Uncharacterized protein.
    
 
 0.691
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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