STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tecpr2Tectonin beta-propeller repeat containing 2. (1349 aa)    
Predicted Functional Partners:
vps41
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
   
   0.952
vps16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
    
 
 0.938
vps18
VPS18 core subunit of CORVET and HOPS complexes.
    
 
 0.912
vps33a
VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.
    
 
 0.765
asmtl
Acetylserotonin O-methyltransferase-like.
      
 0.758
prc1
VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family.
    
 
 0.741
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.
    
 
 0.725
epg5
Ectopic P-granules autophagy protein 5 homolog (C. elegans).
   
  
 0.647
hps3
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1.
   
 
 0.641
trappc11
Trafficking protein particle complex 11.
      
 0.619
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.