STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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LOC103459268Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1730 aa)    
Predicted Functional Partners:
LOC103464608
Calcium channel, voltage-dependent, alpha 2/delta subunit 2b.
   
 0.885
LOC103459225
Calcium channel, voltage-dependent, alpha 2/delta subunit 1a.
   
 0.885
cacna2d2
Calcium channel, voltage-dependent, alpha 2/delta subunit 2a.
   
 0.885
cacna2d1
Calcium voltage-gated channel auxiliary subunit alpha2delta 1.
   
 0.885
Unc79
Uncharacterized protein.
   
 0.878
CACNG1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.845
LOC103469269
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.845
cacnb2
Calcium channel, voltage-dependent, beta 2a.
   
 0.830
LOC103479890
Calcium channel, voltage-dependent, beta 2b.
   
 0.752
cacnb4
Calcium channel, voltage-dependent, beta 4a subunit.
   
 0.746
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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