Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kdsr3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (359 aa)    
Predicted Functional Partners:
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
     
 0.995
LOC103460525
Serine palmitoyltransferase, long chain base subunit 2a.
     
 0.979
sptlc3
Serine palmitoyltransferase, long chain base subunit 3.
     
 0.979
LOC103457821
Serine palmitoyltransferase, long chain base subunit 2b.
     
 0.979
asah1
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
     
 0.957
sphk2
Sphingosine kinase 2.
     
 0.955
SPHK1
Sphingosine kinase 1.
     
 0.952
SPHK1-2
Sphingosine kinase 1.
     
 0.952
cers6
Ceramide synthase 6.
     
 0.950
cers5
Ceramide synthase 5.
     
 0.950
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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