STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000006179Si:ch73-127m5.1; Belongs to the peptidase S1 family. (758 aa)    
Predicted Functional Partners:
bop1
Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
      
 0.577
LOC103474423
Sodium channel, voltage-gated, type IV, beta a.
      
 0.576
mgat5
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase.
    
 0.527
agrn
Agrin.
   
 0.511
crbn
Cereblon.
      
 0.503
apip
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
      
 0.465
serpini1
Serpin peptidase inhibitor, clade I (neuroserpin), member 1; Belongs to the serpin family.
    
 0.442
ENSPREP00000014094
NDK domain-containing protein.
    
 0.433
musk
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.415
aasdh
Aminoadipate-semialdehyde dehydrogenase.
     
 0.404
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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