STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
chd1Chromodomain helicase DNA binding protein 1. (1751 aa)    
Predicted Functional Partners:
ssrp1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.737
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.700
rtf1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.700
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.650
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 
 0.646
arid4b
Translocase of outer mitochondrial membrane 20.
   
 0.597
syk
Tyrosine-protein kinase.
    
 0.585
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
      
 0.581
LOC103462559
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
      
 0.577
ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.577
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.