Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
has1Hyaluronan synthase 1. (572 aa)    
Predicted Functional Partners:
dele1
Uncharacterized protein.
  
 0.752
cpvl
Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.
    
 
 0.671
ugdh
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.657
hacl1
2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family.
  
 0.621
ilvbl
IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family.
  
 0.621
hyal1
Hyaluronidase.
      
 0.572
LOC103475867
Lysine (K)-specific demethylase 6B, b.
  
 0.553
LOC103475798
Lysine (K)-specific demethylase 6A, like.
  
 0.553
kdm6b
Lysine (K)-specific demethylase 6B, a.
  
 0.553
kdm6a
Lysine (K)-specific demethylase 6A.
  
 0.553
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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