Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC103465720RIC3 domain-containing protein. (344 aa)    
Predicted Functional Partners:
unc50
Unc-50 homolog (C. elegans).
      
 0.806
pink1
PTEN induced kinase 1.
      
 0.806
ENSPREP00000020277
RBR-type E3 ubiquitin transferase.
      
 0.758
pla2g6
Phospholipase A2, group VI (cytosolic, calcium-independent).
      
 0.751
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
      
 0.738
synj1
Synaptojanin 1.
     
 0.731
spg11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.729
DNAJC13
DnaJ heat shock protein family (Hsp40) member C13.
      
 0.728
atxn2
Ataxin 2.
      
 0.727
LOC103467077
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
    
 
 0.726
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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