STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC1034766101-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1127 aa)    
Predicted Functional Partners:
LOC103458452
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.605
LOC103463549
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.605
LOC103470235
Uncharacterized protein.
    
 0.605
LOC103470237
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.605
edn1
Endothelin 1.
     
 0.569
acss2
Acetyl-coenzyme A synthetase.
      
 0.560
LOC103457587
Acetyl-coenzyme A synthetase.
      
 0.560
LOC103463548
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.536
LOC103460996
Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
      
 0.531
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
  
  
0.491
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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