STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC1034766101-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1127 aa)    
Predicted Functional Partners:
inpp5a
Inositol polyphosphate-5-phosphatase L.
   
 
 0.918
ENSPREP00000018101
ANF_receptor domain-containing protein.
     
 0.915
LOC103461115
G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family.
     
 0.915
casr
Calcium-sensing receptor.
     
 0.915
calm2
Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family.
     
 0.910
inpp1
Si:ch211-160o17.2.
    
 0.910
mtm1
Myotubularin 1.
     
 0.906
LOC103469372
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.903
itgb3
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.903
pikfyve
Phosphoinositide kinase, FYVE finger containing.
     
 0.901
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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