aptx protein (Poecilia reticulata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

aptx

Aprataxin. (303 aa)

Predicted Functional Partners:

xrcc1

0.985

hus1

0.932

tdp1

0.931

Xrcc4

0.918

parp1

0.906

aplf

0.898

parp2

0.884

lig3

0.865

lig4

0.743

pnkp

0.736

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Xrcc4	aplf	ENSPREP00000006019	ENSPREP00000006962	Uncharacterized protein.	Uncharacterized protein.	0.912
Xrcc4	aptx	ENSPREP00000006019	ENSPREP00000006303	Uncharacterized protein.	Aprataxin.	0.918
Xrcc4	lig3	ENSPREP00000006019	ENSPREP00000020895	Uncharacterized protein.	DNA ligase.	0.753
Xrcc4	lig4	ENSPREP00000006019	ENSPREP00000010705	Uncharacterized protein.	DNA ligase.	0.985
Xrcc4	pnkp	ENSPREP00000006019	ENSPREP00000011491	Uncharacterized protein.	Polynucleotide kinase 3'-phosphatase.	0.777
Xrcc4	xrcc1	ENSPREP00000006019	ENSPREP00000023427	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.577
aplf	Xrcc4	ENSPREP00000006962	ENSPREP00000006019	Uncharacterized protein.	Uncharacterized protein.	0.912
aplf	aptx	ENSPREP00000006962	ENSPREP00000006303	Uncharacterized protein.	Aprataxin.	0.898
aplf	hus1	ENSPREP00000006962	ENSPREP00000015273	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.763
aplf	lig3	ENSPREP00000006962	ENSPREP00000020895	Uncharacterized protein.	DNA ligase.	0.986
aplf	lig4	ENSPREP00000006962	ENSPREP00000010705	Uncharacterized protein.	DNA ligase.	0.983
aplf	parp1	ENSPREP00000006962	ENSPREP00000001596	Uncharacterized protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.983
aplf	parp2	ENSPREP00000006962	ENSPREP00000002153	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.975
aplf	pnkp	ENSPREP00000006962	ENSPREP00000011491	Uncharacterized protein.	Polynucleotide kinase 3'-phosphatase.	0.814
aplf	tdp1	ENSPREP00000006962	ENSPREP00000006602	Uncharacterized protein.	Tyrosyl-DNA phosphodiesterase 1.	0.972
aplf	xrcc1	ENSPREP00000006962	ENSPREP00000023427	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.988
aptx	Xrcc4	ENSPREP00000006303	ENSPREP00000006019	Aprataxin.	Uncharacterized protein.	0.918
aptx	aplf	ENSPREP00000006303	ENSPREP00000006962	Aprataxin.	Uncharacterized protein.	0.898
aptx	hus1	ENSPREP00000006303	ENSPREP00000015273	Aprataxin.	Checkpoint protein; Belongs to the HUS1 family.	0.932
aptx	lig3	ENSPREP00000006303	ENSPREP00000020895	Aprataxin.	DNA ligase.	0.865