Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
p4ha2Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2. (544 aa)    
Predicted Functional Partners:
pycr3
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
     
 0.925
LOC103469886
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 
 0.906
LOC103473756
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 
 0.906
prodh2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 
 0.906
LOC103465458
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
     
 0.905
LOC103468854
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
     
 0.905
lap3
Leucine aminopeptidase 3.
     
 0.900
dao
D-amino-acid oxidase, tandem duplicate 2.
     
 0.803
LOC103462811
Protein disulfide-isomerase.
   
 0.721
p4hb
Protein disulfide-isomerase.
   
 0.721
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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