STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103464516Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)    
Predicted Functional Partners:
LOC103472243
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.993
gnat1
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.
   
 0.981
LOC103467179
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
 0.976
LOC103464572
Rhodopsin.
    
 0.963
LOC103464571
Rhodopsin.
    
 0.963
LOC103481632
Regulator of G protein signaling 9b.
   
 0.963
LOC103468274
Regulator of G protein signaling 9a.
   
 0.963
rho
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
    
 0.963
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
  
  
 
0.900
LOC103462943
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
   
   0.889
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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