STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hat1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (379 aa)    
Predicted Functional Partners:
rbbp4
Retinoblastoma binding protein 4.
   
 0.968
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 0.968
NASP
Nuclear autoantigenic sperm protein.
   
 
 0.948
nasp
Nuclear autoantigenic sperm protein (histone-binding).
   
 
 0.948
bap1
Ubiquitin carboxyl-terminal hydrolase.
   
 
 0.941
orc3
Origin recognition complex, subunit 3.
   
 
 0.934
orc4
Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.
    
 
 0.930
wdr73
WD repeat domain 73.
   
 0.921
orc5
Origin recognition complex, subunit 5.
    
 
 0.916
orc2
Origin recognition complex, subunit 2.
   
 
 0.903
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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