STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpsf6Cleavage and polyadenylation specific factor 6. (586 aa)    
Predicted Functional Partners:
nudt21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 0.985
Tnpo3
Transportin 3.
   
 0.941
Pcf11
CID domain-containing protein.
    
 0.927
CPSF7
Cleavage and polyadenylation specific factor 7.
  
  
 
0.904
cstf2
Cleavage stimulation factor, 3' pre-RNA, subunit 2.
   
 0.877
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.823
cstf3
Cleavage stimulation factor, 3' pre-RNA, subunit 3.
   
 0.805
cstf1
Cleavage stimulation factor, 3' pre-RNA, subunit 1.
    
 0.794
cpsf1
Cleavage and polyadenylation specific factor 1.
   
 0.778
sympk
Symplekin.
   
 0.773
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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