Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hmga2Uncharacterized protein. (115 aa)    
Predicted Functional Partners:
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6.
    
   0.949
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.913
hmga1
Uncharacterized protein.
   
 0.870
ENSPREP00000032744
Retinoblastoma 1.
    
 0.741
Suox
Sulfite oxidase.
      
 0.725
chaf1a
Chromatin assembly factor 1, subunit A (p150).
    
   0.655
parp2
Poly [ADP-ribose] polymerase.
    
 
 0.645
LOC103457646
Lin-28 homolog B (C. elegans).
      
 0.624
ENSPREP00000014491
Zinc finger and AT hook domain containing.
    
 
 0.606
LOC103475870
Nucleophosmin 1a.
    
   0.605
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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