STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccnd3Cyclin D3; Belongs to the cyclin family. (198 aa)    
Predicted Functional Partners:
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.974
ENSPREP00000023356
Retinoblastoma-like 1 (p107).
    
 0.967
LOC103466787
Retinoblastoma-like 2 (p130).
    
 0.967
ENSPREP00000032744
Retinoblastoma 1.
    
 0.967
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.964
cdk4
Cyclin-dependent kinase 4.
   
 0.964
LOC103465183
Cyclin-dependent kinase inhibitor 1A.
   
 0.958
LOC103459498
Cyclin-dependent kinase inhibitor 1D.
   
 0.955
LOC103469340
Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily.
   
 0.947
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.934
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.