STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000006496MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (285 aa)    
Predicted Functional Partners:
LOC103482478
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.883
LOC103459742
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.883
LOC103465012
Ig-like domain-containing protein.
    
 0.860
ENSPREP00000008622
Protein disulfide isomerase family A, member 3.
    
  0.807
LOC103479782
Calreticulin.
    
 0.800
LOC103464072
Calreticulin.
    
 0.800
LOC103472572
Protein disulfide-isomerase.
    
  0.742
rpa2
Replication protein A2.
   
 0.680
LOC103465013
IGv domain-containing protein.
     
 0.656
ENSPREP00000003577
TAP binding protein (tapasin), tandem duplicate 2.
   
 0.545
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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