tdp1 protein (Poecilia reticulata) - STRING interaction network

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Score

tdp1

Tyrosyl-DNA phosphodiesterase 1. (622 aa)

Predicted Functional Partners:

lig3

0.990

polb

0.981

xrcc1

0.978

aplf

0.972

ercc4

0.946

aptx

0.931

tdp2

0.923

apex1

0.901

mus81

0.891

fancm

0.891

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
apex1	aptx	ENSPREP00000021137	ENSPREP00000006303	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Aprataxin.	0.618
apex1	ercc4	ENSPREP00000021137	ENSPREP00000024474	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Excision repair cross-complementation group 4.	0.954
apex1	fancm	ENSPREP00000021137	ENSPREP00000029321	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Uncharacterized protein.	0.534
apex1	lig3	ENSPREP00000021137	ENSPREP00000020895	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA ligase.	0.756
apex1	mus81	ENSPREP00000021137	ENSPREP00000023348	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	MUS81 structure-specific endonuclease subunit.	0.530
apex1	polb	ENSPREP00000021137	ENSPREP00000016804	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.996
apex1	tdp1	ENSPREP00000021137	ENSPREP00000006602	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Tyrosyl-DNA phosphodiesterase 1.	0.901
apex1	tdp2	ENSPREP00000021137	ENSPREP00000011497	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Tyrosyl-DNA phosphodiesterase 2b.	0.492
apex1	xrcc1	ENSPREP00000021137	ENSPREP00000023427	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.931
aplf	aptx	ENSPREP00000006962	ENSPREP00000006303	Uncharacterized protein.	Aprataxin.	0.898
aplf	ercc4	ENSPREP00000006962	ENSPREP00000024474	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.524
aplf	lig3	ENSPREP00000006962	ENSPREP00000020895	Uncharacterized protein.	DNA ligase.	0.986
aplf	polb	ENSPREP00000006962	ENSPREP00000016804	Uncharacterized protein.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.970
aplf	tdp1	ENSPREP00000006962	ENSPREP00000006602	Uncharacterized protein.	Tyrosyl-DNA phosphodiesterase 1.	0.972
aplf	xrcc1	ENSPREP00000006962	ENSPREP00000023427	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.988
aptx	apex1	ENSPREP00000006303	ENSPREP00000021137	Aprataxin.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.618
aptx	aplf	ENSPREP00000006303	ENSPREP00000006962	Aprataxin.	Uncharacterized protein.	0.898
aptx	lig3	ENSPREP00000006303	ENSPREP00000020895	Aprataxin.	DNA ligase.	0.865
aptx	polb	ENSPREP00000006303	ENSPREP00000016804	Aprataxin.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.712
aptx	tdp1	ENSPREP00000006303	ENSPREP00000006602	Aprataxin.	Tyrosyl-DNA phosphodiesterase 1.	0.931