| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPREP00000007515 | LOC103475982 | ENSPREP00000007515 | ENSPREP00000006622 | Uncharacterized protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.648 |
| ENSPREP00000007515 | LOC103476686 | ENSPREP00000007515 | ENSPREP00000012673 | Uncharacterized protein. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.958 |
| ENSPREP00000007515 | adsl | ENSPREP00000007515 | ENSPREP00000027762 | Uncharacterized protein. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.674 |
| ENSPREP00000007515 | atic | ENSPREP00000007515 | ENSPREP00000029576 | Uncharacterized protein. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.975 |
| ENSPREP00000007515 | ephx2 | ENSPREP00000007515 | ENSPREP00000021989 | Uncharacterized protein. | Epoxide hydrolase 2, cytoplasmic. | 0.901 |
| ENSPREP00000007515 | fh | ENSPREP00000007515 | ENSPREP00000018243 | Uncharacterized protein. | Fumarate hydratase. | 0.624 |
| ENSPREP00000007515 | gart | ENSPREP00000007515 | ENSPREP00000009460 | Uncharacterized protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.806 |
| ENSPREP00000007515 | gmps | ENSPREP00000007515 | ENSPREP00000024787 | Uncharacterized protein. | Guanine monophosphate synthase. | 0.985 |
| ENSPREP00000007515 | nt5e | ENSPREP00000007515 | ENSPREP00000017485 | Uncharacterized protein. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.959 |
| ENSPREP00000007515 | ppat | ENSPREP00000007515 | ENSPREP00000029819 | Uncharacterized protein. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.607 |
| LOC103475982 | ENSPREP00000007515 | ENSPREP00000006622 | ENSPREP00000007515 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Uncharacterized protein. | 0.648 |
| LOC103475982 | LOC103476686 | ENSPREP00000006622 | ENSPREP00000012673 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.599 |
| LOC103475982 | adsl | ENSPREP00000006622 | ENSPREP00000027762 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.674 |
| LOC103475982 | atic | ENSPREP00000006622 | ENSPREP00000029576 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.769 |
| LOC103475982 | ephx2 | ENSPREP00000006622 | ENSPREP00000021989 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Epoxide hydrolase 2, cytoplasmic. | 0.901 |
| LOC103475982 | fh | ENSPREP00000006622 | ENSPREP00000018243 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Fumarate hydratase. | 0.624 |
| LOC103475982 | gart | ENSPREP00000006622 | ENSPREP00000009460 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.806 |
| LOC103475982 | gmps | ENSPREP00000006622 | ENSPREP00000024787 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Guanine monophosphate synthase. | 0.860 |
| LOC103475982 | nt5e | ENSPREP00000006622 | ENSPREP00000017485 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.613 |
| LOC103475982 | ppat | ENSPREP00000006622 | ENSPREP00000029819 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.607 |