pms2 protein (Poecilia reticulata) - STRING interaction network

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[Homology]

Score

pms2

PMS1 homolog 2, mismatch repair system component. (822 aa)

Predicted Functional Partners:

mlh1

0.999

msh2

0.999

msh6

0.998

fan1

0.996

msh3

0.989

brip1

0.988

exo1

0.978

pcna

0.967

pold1

0.942

rtel1

0.889

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
brip1	exo1	ENSPREP00000022752	ENSPREP00000027206	BRCA1 interacting protein C-terminal helicase 1.	Exonuclease 1.	0.846
brip1	fan1	ENSPREP00000022752	ENSPREP00000022191	BRCA1 interacting protein C-terminal helicase 1.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.521
brip1	mlh1	ENSPREP00000022752	ENSPREP00000002003	BRCA1 interacting protein C-terminal helicase 1.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.988
brip1	msh2	ENSPREP00000022752	ENSPREP00000007571	BRCA1 interacting protein C-terminal helicase 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.453
brip1	msh6	ENSPREP00000022752	ENSPREP00000034111	BRCA1 interacting protein C-terminal helicase 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.437
brip1	pcna	ENSPREP00000022752	ENSPREP00000018020	BRCA1 interacting protein C-terminal helicase 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.810
brip1	pms2	ENSPREP00000022752	ENSPREP00000006640	BRCA1 interacting protein C-terminal helicase 1.	PMS1 homolog 2, mismatch repair system component.	0.988
brip1	pold1	ENSPREP00000022752	ENSPREP00000020414	BRCA1 interacting protein C-terminal helicase 1.	DNA polymerase.	0.573
exo1	brip1	ENSPREP00000027206	ENSPREP00000022752	Exonuclease 1.	BRCA1 interacting protein C-terminal helicase 1.	0.846
exo1	fan1	ENSPREP00000027206	ENSPREP00000022191	Exonuclease 1.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.451
exo1	mlh1	ENSPREP00000027206	ENSPREP00000002003	Exonuclease 1.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.996
exo1	msh2	ENSPREP00000027206	ENSPREP00000007571	Exonuclease 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.996
exo1	msh3	ENSPREP00000027206	ENSPREP00000018450	Exonuclease 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.935
exo1	msh6	ENSPREP00000027206	ENSPREP00000034111	Exonuclease 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.974
exo1	pcna	ENSPREP00000027206	ENSPREP00000018020	Exonuclease 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.995
exo1	pms2	ENSPREP00000027206	ENSPREP00000006640	Exonuclease 1.	PMS1 homolog 2, mismatch repair system component.	0.978
exo1	pold1	ENSPREP00000027206	ENSPREP00000020414	Exonuclease 1.	DNA polymerase.	0.949
exo1	rtel1	ENSPREP00000027206	ENSPREP00000012657	Exonuclease 1.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.846
fan1	brip1	ENSPREP00000022191	ENSPREP00000022752	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	BRCA1 interacting protein C-terminal helicase 1.	0.521
fan1	exo1	ENSPREP00000022191	ENSPREP00000027206	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Exonuclease 1.	0.451